AMD and Nutanix have announced a multi-year strategic partnership to jointly develop an open, full-stack AI infrastructure platform designed to power agentic AI applications.

Dan McNamara, senior vice president and general manager of Compute and Enterprise AI at AMD, said: “Through our partnership with Nutanix, we’re building a scalable, full-stack AI platform rooted in openness, designed to give enterprises and service providers the flexibility to innovate, extend and grow AI deployments across Enterprises.”
Advancing an open and scalable platform for enterprise AI
The partnership entails both companies developing an open solution for agentic AI platforms through high-performance infrastructure, supported by a broad set of OEM partners.
This is achieved by optimising the Nutanix Cloud and Nutanix Kubernetes Platforms on AMD EPYC CPUs and AMD Instinct GPUs. The AMD ROCm software ecosystem and the AMD Enterprise AI platform will also integrate into Nutanix AI full-stack solutions.
The first jointly developed agentic AI platform from this partnership is expected to come to market beginning in late 2026. It aims to enable enterprises to deploy open-source and commercial AI models without dependency on vertically integrated AI stacks.
Further, it seeks to provide high-performance inference acceleration powered by AMD Instinct GPUs and EPY CPUs, high-core-density compute and orchestration through AMD EPYC processors, and unified lifecycle management via Nutanix Enterprise AI.
Investing in joint engineering initiatives and collaboration
AMD will also invest $150 million in Nutanix common stock at a purchase price of $36.26 per share, and fund up to $100 million for Nutanix to support joint engineering initiatives and go-to-market collaboration to accelerate the adoption of AMD and the Nutanix-powered agentic AI platform.

“Our partnership with AMD reflects a shared vision for scalable, production-ready AI infrastructure,” said Tarkan Maner, president and chief commercial officer, Nutanix. “Together, we are delivering full-stack, integrated platforms optimised for inference and agentic applications across hybrid environments for enterprises and service providers.”
